Many volunteers around the world promise to raise funds for cancer research and cancer charity organizations. Hundreds of thousands of caregivers, medicine research, prescription, diagnosis, manufacturing, etc. are working more in the industry. A huge company spends a huge cost on cancer research. Did you spend billions of what cancer research revealed for so long?
Understanding of cancer had periodic breakthrough, but there was little progress in treatment. The study of modern cancer began when the scientists separated leukemia cells of experimental mice and substances that kill cancer cells that are growing in Petri dishes from the 1940 's to the 50' s. The early success of chemotherapy, although often applied to only 5% of cancer treatment, expanded the pace and underwent exposure to many media.
Providing services to mankind by solving its major diseases has the status of a celebrity, there are many pride and air related to things like Hollywood. Cancer research has received high acclaim and scientific therapies have been discovered to obtain broad cognition, such as the HPV-16 trial, but it applies only to a small proportion of cancer treatments. The mass media hype is part of the problem of what happens to cancer. Early discovery had hoped that there would be all treatments of cure that finders would become famous by cure of cancer worldwide, "magical bullets". The idea is derived from aspirin. Aspirin is the original bullet that feels pain like a magic and reduces pain.
In the 1950s and 60s, a huge and expensive research project was established to examine whether any known substances are tested and will affect cancer cells. You may remember the discovery of Madagascar's Periwinkle (Catharansus Roseus). Alkaloids (vinblastine and vincristine) are also used in chemotherapy today. Taxol, a treatment for ovarian cancer and breast cancer originally originated from trees of the Pacific Judaism. "Etoposide" for treatment of testicular cancer and small cell lung cancer is derived from an apple of May. Jonathan Hartwell's "plants used for cancer" has been identified from medicine and civil sources to treat cancer, about half of which have some effect on in vitro cancer cells As shown in FIG.
When these plants are made into synthetic drugs, a single chemical substance is separated and the rest of the plant is usually discarded. Pharmaceutically active molecules are extracted from plants and modified until chemically unique. Later, the compound is patented and tested given the brand name.
The first phase is generally tested in animals, in the second stage the dose level is determined and in the third stage it is tested against people. Under the approval of the UK Federal Drug Administration (US) or the UK pharmaceutical and healthcare product regulatory authority (MHRA), the development cost of new drugs may reach up to $ 500 million, eventually being a consumer.
In addition to "research oriented" research such as discovery of chemical substances affecting cancer cells, basic research continues to differ between normal cells and cancer cells. In the past 30 years, this study has revealed much about our nature, but there is no cure yet. The following is the current trend of scientific research on cancer.
Antibody induction therapy: This is the original "magic bullet". Cancer researchers use monoclonal antibodies to carry poison directly to cancer cells without harming others.
Chronobiology: Many of what happens in our bodies are managed by cycles from women's monthly cycles to brain wave cycles. Human health depends on interaction cycles tailored to perception, respiration, reproductive and regenerative behavior. Chrono biology analyzes these cycles in relation to different times like day and night. Hormones, including stress and growth hormone, have their own cycle. For example, they may have the highest activity in the morning and quiet in the evening. The cancer cells no longer seem to follow the same cycle rate as normal cells.
Anti-telomerase: A part of the cell called telomerase dominates the life cycle of the cell and how many times it grows. Several cancer cells escape this control and can increase the number of divisions and become 'immortal'. Researchers hope to control cancer cells by stopping the action of telomerase.
Antiangiogenesis: Secondary tumors (metastases) can grow new blood vessels to supply tumors to cells surrounding them and can supply oxygen and nutrients for proliferating cancers. This process is called angiogenesis, and the study here is to find a way to stop the signal on normal cells that initiate the process.
Anti-adhesion molecules: cancer cells become clumps, unlike Petri dishes that are in a flat arrangement. When there are cell masses, they seem to have quality to withstand treatment. This study considers ways to prevent cells from clumping together by dissolving lumps for more effective treatment.
Anticancer Gene Product: A specific part of DNA called an oncogene that plays an important role in promoting cancer growth. Drugs that interfere with the production of oncogenes can be useful for the future treatment of cancer.
Gene therapy: Research on the use of tumor suppressor genes is emphasized as an important element in the British National Cancer Plan. Originally, DNA defects are inserted to replace lost or damaged genes, which can presumably prevent cancer from occurring in high-risk individuals.
Vaccine: Very quietly, the search for general treatment of cancer is taking precedence over the discovery of vaccines. In the case of specific, chaotic conditions that cause cancer to individuals, the overall idea of 'same for everyone' treatment or cure is counteracted. After spending billions on the study of the Holy Grail of cancer treatment, the search for vaccines began.
In the recent American cancer immunology society, lectures were presented on the latest immunology topics such as cancer immunodiagnosis, immunostimulation, cancer antigen discovery, monitoring and analysis of immunologic responses to human cancer, development of cancer vaccines .
The Cancer Vaccine Collaborative (CVC) began with excitement. This is a unique research program to improve the development method of cancer vaccine based on the cooperation of 6 medical centers in New York and medical institutions in Minnesota state. The aim of their research is to find ways to effectively immunize cancer with a vaccine using "behavioral research".
Vaccines made from donor's blood have been proven to work for several cancers. In the experiment of bone marrow transplantation, it is found that there are about 40,000 types of tissues, making finding a match difficult. Usually, perfect matches can only be found within the patient's direct family. Incorrect matches may create a host of secondary discomfort. Scientists have found a way to train killer T cells harvested from either the host or donor to more effectively attack the cancer cells. They noticed that donor killer T cells, which have already been "primed" for certain cancers (eg, donor somatic cells remember the disease) can be very effective. It may take years to prove the effectiveness, reliability, safety and efficacy of this treatment. Harvesting our own or donor cell's natural immunity with the help of genetic engineering can be a major player against modern immune attack display.
Increased Screening: This type of research is seeing genetically identifying potentially high risk for certain types of cancer, and in part it is the preparation of possible vaccines. Genetic counseling will be a contributor to the 21st century healthcare based on healing based on disease prevention.
Combination: The study of West Germany (Grossart-Maticek) claims that, as with most chronic disease patterns, there is no single cause of cancer. It shows that disease has an environmental, psychological, spiritual dimension. The meaning is that treatments must be at the same level and there is no single cause, single treatment may be ineffective. This observation is often linked to the position of many holistic practitioners with a broader health perspective than traditional health care workers.
Dr. Robert Bachman is an experienced cancer researcher and author of a useful book, "What You Need To Know About Cancer". He is summarizing what he is seeing as the current position of scientific cancer research:
"There are quite a lot of ways to see cancer cells in the laboratory.We are cultivating thousands of cancer cells in dishes, many of which can be grown and healed in experimental breeding mice. There are various ways to observe and test the cells of cells, such as growth of cells, ability to produce different substances, susceptibility to chemotherapeutic drugs and resistance to others, growth factors, genetic material (eg of the immune system) The ability to influence cells, the ability to invade and invade membranes, their structure under the electron microscope, and now few can do whether cell surfaces have hundreds of something A complete list of ways in which cancer cells are examined will probably be longer than t All of his books but there are troubles here.The accumulated experience is wonderful, cancer (In the light of current knowledge) will be more complicated than ever in any experimental system.
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